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Jeanway

~ Biological Warfare ~

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How many times have you heard about this lately? Especally from guys and girls who came back from fighting in a war? They have all these vague symptoms that doctors can't explain, especially the government doctors. Recently on Enterprise it was mentioned a few times as well. And terrorists are releasing this stuff all over the world on unsuspecting civilians.

 

Here is one of them:

 

Brucellois (Brucella suis)

 

Brucellosis is an infectious disease caused by the bacteria of the genus Brucella. These bacteria are primarily passed among animals, and they cause disease in many different vertebrates. Various Brucella species affect sheep, goats, cattle, deer, elk, pigs, dogs, and several other animals. Humans become infected by coming in contact with animals or animal products that are contaminated with these bacteria. In humans brucellosis can cause a range of symptoms that are similar to the flu and may include fever, sweats, headaches, back pains, and physical weakness. Sever infections of the central nervous systems or lining of the heart may occur. Brucellosis can also cause long-lasting or chronic symptoms that include recurrent fevers, joint pain, and fatigue.

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And here are a few more:

 

Smallpox (Variola virus)

 

Smallpox infection was eliminated from the world in 1977.

 

Smallpox is caused by Variola virus. The incubation period is about 12 days (range: 7 to 17 days) following exposure. Initial symptoms include high fever, fatigue, and head and back aches. A characteristic rash, most prominent on the face, arms, and legs, follows in 2-3 days. The rash starts with flat red lesions that evolve at the same rate. Lesions become pus-filled and begin to crust early in the second week. Scabs develop and then separate and fall off after about 3-4 weeks. The majority of patients with smallpox recover, but death occurs in up to 30% of cases.

 

Smallpox is spread from one person to another by infected saliva droplets that expose a susceptible person having face-to-face contact with the ill person. Persons with smallpox are most infectious during the first week of illness, because that is when the largest amount of virus is present in saliva. However, some risk of transmission lasts until all scabs have fallen off.

 

Routine vaccination against smallpox ended in 1972. The level of immunity, if any, among persons who were vaccinated before 1972 is uncertain; therefore, these persons are assumed to be susceptible.

 

Vaccination against smallpox is not recommended to prevent the disease in the general public and therefore is not available.

From Facts About Smallpox by the Centers for Disease Control and Prevention

 

 

Anthrax (bacillus anthracis)

 

Anthrax is an acute infectious disease caused by the spore-forming bacterium Bacillus anthracis. Anthrax most commonly occurs in hoofed mammals and can also infect humans.

 

Symptoms of disease vary depending on how the disease was contracted, but usually occur within 7 days after exposure. The serious forms of human anthrax are inhalation anthrax, cutaneous anthrax, and intestinal anthrax.

 

Initial symptoms of inhalation anthrax infection may resemble a common cold. After several days, the symptoms may progress to severe breathing problems and shock. Inhalation anthrax is often fatal.

 

The intestinal disease form of anthrax may follow the consumption of contaminated food and is characterized by an acute inflammation of the intestinal tract. Initial signs of nausea, loss of appetite, vomiting, and fever are followed by abdominal pain, vomiting of blood, and severe diarrhea.

 

Direct person-to-person spread of anthrax is extremely unlikely, if it occurs at all. Therefore, there is no need to immunize or treat contacts of persons ill with anthrax, such as household contacts, friends, or coworkers, unless they also were also exposed to the same source of infection.

 

In persons exposed to anthrax, infection can be prevented with antibiotic treatment.

 

Early antibiotic treatment of anthrax is essential-delay lessens chances for survival. Anthrax usually is susceptible to penicillin, doxycycline, and fluoroquinolones.

 

An anthrax vaccine also can prevent infection. Vaccination against anthrax is not recommended for the general public to prevent disease and is not available.

From Facts About Anthrax by the Centers for Disease Control and Prevention

 

 

Plague, Bubonic (Yersinia pestis)

 

Plague is an infectious disease of animals and humans caused by the bacterium Yersinia pestis. Y. pestis, is found in rodents and their fleas in many areas around the world.

 

Pneumonic plague occurs when Y. pestis infects the lungs. The first signs of illness in pneumonic plague are fever, headache, weakness, and cough productive of bloody or watery sputum. The pneumonia progresses over 2 to 4 days and may cause septic shock and, without early treatment, death.

 

Person-to-person transmission of pneumonic plague occurs through respiratory droplets, which can only infect those who have face-to-face contact with the ill patient.

 

Early treatment of pneumonic plague is essential. Several antibiotics are effective, including streptomycin, tetracycline, and chloramphenicol. There is no vaccine against plague. Prophylactic antibiotic treatment for 7 days will protect persons who have had face-to-face contact with infected patients

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If there is any one area that as a species we are most vulnerable, it's biological. It's already been said that if there is any one thing that can threaten the continued dominance of humankind on this planet, it is the virus or any biological agent, that we have no natural defense for. If a virus mutates or is caused to mutate by artificial means, i.e. biological warfare agents, it could cause the human race to fall. It doesn't even have to affect humans. A biological agent could be introduced to the food chain, beginning a cascade failure of every living thing on the planet. As the lower stratas of the chain begin to crumble and break apart, those higher up on the chain will fall as easily as a building that loses it's foundational support. As humans, we are actually living on the knife's edge when it comes to attacking and rejecting any foreign element introduced into our immune system. All it takes is one microscopic bug that our bodys are totally unfamiliar with to begin the downfall of mankind. And it's not the first time we have faced this. History has already shown that the first colonists brought the smallpox bacteria to this continent which wiped out numerous tribes who had no defense against this new disease. The flu pandemic of 1918, which swept the world, accounted for over 11 million deaths. With our packed population centers of today, any new disease introduced would be deadly and quick and most likely, unstoppable. The stuff of science fiction movies such as "28 Days Later", or "12 monkeys", or even that classic "Andromeda Strain", could be much closer to reality than we all care to think. This nightmare could become reality in a split second.

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I've read a couple of interesting books in this topic.

 

The Hot Zone about USAMRIID and some of the more infections diseases like Ebola and Marbury. There was an ebola infected monkey that escaped containment in a subdivision in Reston, VA. People are in the building in those Hazmat suits chasing down a monkey while children are playing in a playground several yards away. Scary stuff - but they used Chlorox bleach to hose down the ebola carcases and I decided to keep lots of Chlorox on hand - I mean if USAMRIID (the military version of the CDC) uses it for ebola I guess it will clean my bathroom. :nono:

 

The book suggested that ebola wouldn't really be the type of disease to wipe out the planet because people died so quickly outbreaks could be contained - unlike smallpox which had longer incubation.

 

I also read a book about the history of smallpox. There are two places in the world that still have the smallpox virus - the CDC in Atlanta and the Russian equivalent. At least that's how it is supposed to be but according to the book - the failing Soviet Union may have sold a "modified" version to Iraq when it was selling off everything to raise capital. (of course the USSR wasn't supposed to be creating a new strain) A modified version wouldn't respond to the vacccine we have in stock. If that ever gets loose it will be devasting.

 

Both books were very interesting.

 

But I do suspect despite all our "achievements" it will be a microscopic organism that brings us down.

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The hot zone is very good. More biological warfare includes botulinum. Nice that a few millionths of a gram can kill you within 45 minutes... Note the ability of a cup to kill off the human race...

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Heck, even chicken pox can be a horrid sickness is releases upon the general public. Yes, I know that most children get it and recover, but there's also a lot of children who don't recieve it. In adults it has a higher fatality rate than children. One of the reasons I'm concerned about such an occurence is the fact that I have never had chicken pox. I'm 23, and if I was to contract it now, it would probably kill me. My lungs and heart are in bad shape due to smoking, and my liver is in sad condition due to my drinking habits. Fair to say, such a virus would most likely kill me. And there's plenty of adults who've never had chicken pox.

 

While it may not be fatal to a society, it can very likely prove to be a scare among the general population, which can result in panics, roits, and who knows what else, if released over a large area.

 

Of course, I may be wrong. But one never knows.

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QUOTE, WISHFIRE:

 

"I'm 23, and if I was to contract it now, it would probably kill me. My lungs and heart are in bad shape due to smoking, and my liver is in sad condition due to my drinking habits."

 

Geeze wf. It can't be THAT bad. I mean your only 23. :nono: Take care of yourself, will ya? :nono: :(

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I think you can still get the chicken pox vaccine as an adult. I had measles as an adult because I apparently didn't get the vaccine as a kid- it did hurt my vision some.

 

We were just talking about how the State of Florida requires kids to have the chicken pox vaccine in order to attend school. (not all states do) - I didn't realize it was that bad. I had a mild case when I was a kid.

 

Does anyone watch that show medical investigations? This thread reminds me of that.

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QUOTE, WISHFIRE:

 

    "I'm 23, and if I was to contract it now, it would probably kill me. My lungs and heart are in bad shape due to smoking, and my liver is in sad condition due to my drinking habits."

 

Geeze wf. It can't be THAT bad. I mean your only 23. :frusty: Take care of yourself, will ya? :huh:  :angry:

282382[/snapback]

 

I tried, but then I sorta gave up when I was making $20 an hour and my boss decided to cheat me out of several thousand dollars my saying I stole from him. I know for a fact that his "evidence" is made-up and altered, but I don't have the physical proof. Grrr...

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. In adults it has a higher fatality rate than children. One of the reasons I'm concerned about such an occurence is the fact that I have never had chicken pox. I'm 23, and if I was to contract it now, it would probably kill me.

 

I've been there. When I was growing up I had every childhood sickness that you could get with the exception of chicken pox. It just didn't sweep my neighborhood. In 1992, my then 5 year old daughter brought it home from daycare and it never occurred to me that I was suseptible. Ten days later the pox broke out. On my 35th birthday, I was rushed to by ambulance and admitted to the hospital and immediately put into intensive care and was completely isolated from everyone else in the wing because the chicken pox was still contagious. The pox almost killed me. The weekend before being admitted, I had a temperature well over 105 degrees and was completely incoherent about my surroundings or what was happening to me. The pox opened me up for a staph infection due to the weeping of the pox and attacked my saliva glands in my neck and face. I looked like someone took a football, cut it down the middle lengthwise and plastered it to my face. I had a traceotomy (?) tray next to my bed because the doctors were fearful that the swelling would close off my windpipe and I would suffocate to death. For five days, I'm told, I was fed the strongest anti-biotic available at the time, directly into my veins. The doctors I had, had never seen anything like me at all and I've no doubt that I may be written up in a medical journal somewhere. After a whole week of being fed nothing but the strongest drugs they could give me without killing me, the disease was finally beaten and I was allowed to finally go home but it still took another six months before I was declared cured. It was the scariest moment of my entire life. I still don't have a clear recollection of those two weeks, it was almost dreamlike in a sense. Because of this, I'm all for the developement of a chicken pox vacine. The scariest part of this for anyone is the fact that if you get infected, the disease has an incubation period of about a week to ten days so if you get exposed and you've never had it, you don't know you're going to get sick until it breaks and by then, you could already be doomed. To anyone who never caught the disease, that thought alone should cause you to shake in your boots.

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I found the following online and I thought it was interesting. I'm always amazed how a lot of people think that everything that happens is somehow new. It's all been done before, the only thing new are the calendars. B)

 

*warning, it's kind of long so I put it in a spoiler*

 

Click For Spoiler
Evidence can be found for the existence of forms of chemical and biological warfare in ancient and classical times. The evidence for chemical and toxin warfare is the clearest. Solon of Athens is said to have used hellebore roots (a purgative) to poison the water in an aqueduct leading from the Pleistrus River around 590 B.C. during the siege of Cirrha.[1] Writings of the Mohist sect in China dating from the Fourth Century B.C. tell of the use of ox-hide bellows to pump smoke from furnaces in which balls of mustard and other toxic vegetable matter were being burnt into tunnels being dug by a beseiging army to discourage the diggers. The use of a toxic cacodyl (arsenic trioxide) smoke is also mentioned in early Chinese manuscripts. Sparta used the toxic smoke generated by burning wood dipped in a mixture of tar and sulfur during one of its periodic wars with Athens.

Many early accounts portray outbreaks of disease in invading armies or among conquerers as divine intervention, perhaps an indication of the terrible effects of disease coupled with the lack of understanding of its causes. This confusion between divine and secular causes does make it difficult to distinguish when an outbreak was natural and when it was, so to speak, assisted. The misfortunes of the Philistines after they captured the Ark of the Covenant from the Israelites more than three thousand years ago (told of in I Samuel 4:10 to 6:12) provide an example. The Philistines conveyed the Ark to the city of Ashdod (the home of one of the rulers of the Philistines) and placed it beside the statue of their god, Dagon, in the temple there. In short order, the statue of Dagon fell down (twice) and the population was afflicted with "tumors." The people of Ashdod then decided that the best thing to do was send the Ark, the arrival of which had seemed to precipitate their problems, to Gath (the capital city of a different Philistine ruler). No sooner did the Ark arrive in Gath than "the people of the city, both young and old, [were afflicted] with an outbreak of tumors". The people of Gath quickly decided that the best thing to do was to send the Ark to Ekron (the capital of yet another of the rulers of the Philistines), where we are told that, as the Ark was brought into the town, the people cried out that "They have brought the ark of the god of Israel around to us to kill us..." A plague of tumors also broke out in Ekron, and it is perhaps not surprising at this point that the Philistines decided to send the Ark back (or at least out of Philistine territory), accompanied by an unusual guilt offering (five gold tumors and five gold rats, the apparent association of the disease with the rats causing many modern scholars to suggest that the tumors were the buboes of bubonic plague). The story as related suggests that the disease appeared by intention (albeit it not the intention of men), although the coincidence of the plague breaking out along the Ark's travels may, of course, also be explained by a natural outbreak, possibly carried from city to city by the escort of the Ark. Diseases that are considered major potential biological weapons in modern times have been known since antiquity. Smallpox is probably the oldest - it is thought to have existed at least since 10,000 B.C., when the first farming settlements were founded in northeastern Africa. It was first described in the West as the Great Plague of Athens in 430 B.C. The Great Plague would help lead to the downfall of Periclean Athens and thereby demonstrate the effectiveness of disease in influencing human events.

Anthrax and the plague have been implicated as the fifth plague of Egypt in the fifteenth century B.C.

 

It is difficult to be certain about the exact identifications as these diseases affect the soft tissues that decay rapidly after death.

 

Knowledge of the Chinese application of noxious smokes was not hidden from Europe. Formulas for "fire lances" in the Chinese style may be found in Biringucio's 1540 treatise Pirotechnia. Based on surviving accounts, it is clear that the Chinese were the original masters of chemical warfare. It has been suggested that the pursuit of chemical weapons may have originated in the fumigation of dwellings to eliminate fleas (known to have been practiced by the Chinese as long ago as the Seventh century B.C.) or from the Chinese philosophical view that all matter faded into a more tenuous form, which lead them to take special interest in the study of vapors. Whatever the case, Chinese writings contain literally hundreds of recipes for the production of poisonous or irritating smokes for use in war, and many accounts of their use. Thus we know of the arsenic-containing "soul-hunting fog" and the irritating "five-league fog" (formed from a slow-burning gunpowder to which a variety of ingredients, including the excrement of wolves, was added to produce an irritating smoke). The use of a sort of riot control agent (finely divided lime dispersed into the air) is described in a Chinese account of the suppresion of a peasant revolt in 178 A.D. Nor did they neglect delivery systems - descriptions of weapons with such poetic names as the "poison fog magic smoke eruptor" may be found in the artillery manuals of the Chinese army.

ARMIS BELLA NON VENENIS GERI.

"War is fought with weapons, not with poisons."

A declaration of Roman jurists.

The declaration above was made in reaction to the poisoning of wells by their enemies as the Romans tried to conquer the Germanic tribes. In the west, the use of toxic materials was generally viewed with mixed emotions and some disdain (especially when your enemies were doing it). There was also a strong tendency to keep useful knowledge, especially militarily useful knowledge, from wide dissemination. After all, if the knowledge was held by an individual, he could advance himself economically by retaining the secret and offering his services, while states tended to hold knowledge closely to prevent others from using it against them. Nor was there any philosophical reason to investigate vapors and smokes. This meant that, in contrast to China, where the study of chemicals including their military uses was widespread, in Europe the use of chemicals in battle (with the exception of incendiaries of various sorts and, of course, the use of wet vegetable matter to generate smoke screens) was usually the result of an independent local initiative, rather than the result of a logical building on prior experience. While there are many reports of the isolated use of chemical agents in individual battles or sieges, there was no general tradition of their use (again, with the exception of incendiaries and smoke). The secret of Greek fire, the great incendiary weapon of the Byzantines, was held so closely that its composition has been lost to history. Those knowing the secret often responded to inquiries by saying that the formulation had been revealed by an angel to the Constantines, and that any attempt to discover it would provoke the vengeance of God.

It may even have been lost to the Byzantines - when Constantinople fell into the hands of the Crusaders in 1204 A.D., Greek fire was nowhere to be found.

 

Wells have been poisoned by various chemicals or by the simple expedient of dropping human and animal corpses into them for millenia.

The Romans, despite the declaration of their Jurists, were not above poisoning wells when it suited them. For instance, when, after defeating Aristonicus in Asia Minor (Caria), the Romans were faced with guerrilla warfare by the remnants of Aristonicus' army, they poisoned the wells that the guerillas and their supporters used. The result was the end of the war leaving Rome in control of the region.

 

Poisoning of wells also occurred in the 19th Century during the American Civil War and in South Africa during the Boer War and continues to this day with the Kurdish Workers Party (PKK) of Turkey reported to have poisoned wells in Turkish Kurdistan in mid-1997.

As a result, the use of chemical agents in conflicts in Europe was fairly limited through the end of the Renaissance. There was, however, considerable attention paid to poisons. The Roman Emperors, in particular the Julio-Claudian emperors, would gain a attention for poisoning members of their families and others that displeased them. Nor was the practice limited to the Emperors - Juvenal would write of it in his Satires in a way that suggested that it had become a sort of status symbol among the upper classes.

A woman named Locusta would become particularly infamous as a poisoner in Rome; she would also be one of the first to systematically investigate the use of poisons with state (or, at least, Imperial) sponsorship. Convicted for a multiplicity of crimes under Claudius, she was sentenced to death, but the sentence had not been carried out when Claudius died (the delay in the execution of her sentence is said to have been arranged by Agippina, the wife of Claudius and mother of Nero, so that Locusta might prepare a poison for Agrippina to use on Claudius). Subsequently, the new Emperor Nero is supposed to have asked Locusta to prepare a potion for use on Nero's half-brother, Britannicus. Once Brittanicus died, Nero suspended the death penalty and made Locusta his advisor on poisons. In due course, he organized a school of poisoning where she could tutor others and conduct experiments aimed at determining how to poison and how to defend the person of the Emperor against poison. Surviving accounts indicate that many tests were performed on animals and that at least some tests were performed on convicted criminals. (Nero's preferred poison is said to have been cherry laurel water, which contains cyanide.)

 

Poisoning would decline in popularity after the Second Century, but it would never disappear, and would occasionaly enjoy a renewed popularity. For instance, the poisoning of individuals, usually with extracts of plants such as aconite or Belladonna, would be an accepted part of statecraft in the Renaissance, especially in Italy. The meticulous records of the Council of Ten of Venice, for instance, contain considerable information on how victims were selected, poisoners contracted, prices set, and payment made for the completion of the task (indicated by the notation factum in the records). And in France, the use of "inheritance powders" would be widespread until the Poison Affair brought scandal to the court of King Louis XIV and the formation of the burning court (chambre ardente) forced, if not an elimination of poisoning, at least a greater degree of circumspection in its practice. But, for the most part, chemical poisons were employed against individuals, usually for assasination, but sometimes in battle as when poisoned arrows were used, and not in a manner calculated to produce mass casualties in groups. However, accusations of attempts at mass poisonings, especially when seen as useful to make for political ends or during times of stress (as when Jewish communities bore the brunt of attacks for "poisoning" during the plague years) were commonly heard. The use of poisoned projectiles (arrows and, later, bullets) has been widespread:

arrows dipped in blood mixed with manure (Scythian archers, ca. 400 B.C., and others)

arrows dipped in curare (Amazonian Indians)

arrows poisoned with batrachotoxin from frogs (Hawaiian Islanders)

grenade shrapnel contaminated with botulinus toxin (WW II)

ricin-filled pellets (Cold War)

 

In 67 B.C., Pompey was leading a campaign against Mithridates, the king of Pontus. As his troops passed along the roads in the Trebizond region (in modern Turkey), the people of the region, the Heptakometes (who were allied with Mithridates), put out honey as tribute. The honey was a local product, and it contained acetylandromedol, a grayanotoxin (as the bees visited the local rhododendron species). This toxin produced nausea and hallucinations, and perhaps some deaths, among the troops who consumed it, and three maniples of the Roman army were attacked and destroyed while intoxicated.

The Roman commanders should have studied their classics more closely - Xenophon, in his Anabasis, tells of what happened when his troops consumed some of the local honeycomb in the same area in 401 B.C. - although he was luckier than Pompey, as the Persians who were pursuing him did not attack during the four days his army took to recover.

The use of toxic materials in war was not, however, completely absent.

In 187 B.C., the inhabitants of the town of Ambracia in Epirus dealt a setback to Roman soldiers seeking to tunnel under their walls:

Filling a huge jar with feathers, they put fire in it and attached a bronze cover perforated with numerous holes. After carrying the jar into the mine and turning its mouth toward the enemy, they inserted a bellows in the bottom, and by pumping the bellows vigorously they caused a tremendous amount of disagreeable smoke, such as feathers would naturally create, to pour forth, so that none of the Romans could endure it. As a result the Romans, despairing of success, made a truce and raised the siege.

- Cassius Dio, Roman History, Book XIX

Roman commanders were not always on the receiving end, however. And they could be quite inventive.

 

Plutarch, in his Life of Sertorius, tells us of how that worthy soldier dealt with the Characitanes, who had a redoubt formed from a series of caves that seemed impregnable. Noticing that the prevailing winds blew from the North, and that the openings of most of the caves faced the North, Sertonius had his soldiers pile up a mound of earth in front of the redoubt. As the breeze began to blow, he had his soldiers turn the earth over, and his calvary ride over it, raising a cloud of somewhat caustic dust - what might be called a particulate aerosol today - that blew into the caves, blinding and choking the Characitanes. After two days of this treatment, they surrendered, "adding, by their defeat, not so much to the power of Sertorius, as to his renown, in proving that he was able to conquer places by art, which were impregnable by the force of arms".

 

The Romans also practiced anticrop chemical warfare, most famously after the defeat of Carthage, when the fields were sown with salt to help prevent resettlement.

 

The biggest use of chemicals in war in ancient times was in the area of flame weapons. The first use of fire in war probably followed shortly after the discovery of how to make it appear on command. By the Fourth Century B.C., a number of recipes existed for producing incendiary compositions, such as that provided by Aineias in his On the Defense of Fortified Positions, which comprised pitch, sulfur, tow, granulated frankincense, and pine sawdust in sacks which were set alight. Aineias cites as the virtue of this mixture the difficulty of extinguishing it; while the sulfur, at least, would also have produced toxic fumes, this does not seem to have be given any particular import. Indeed, although a variety of mixtures were used containing an astonishing number of additives, the major interest in additives seems to have been related to their perceived value in producing a hotter flame (for instance, salt appears to have been added commonly because it produced a visible orange flame), rather than for the production of choking or irritating smoke.

The most famous incendiary mixture is certainly the Greek fire of the Byzantine Empire (Greek fire is a modern name - the Byzantines called it "sea fire"; their Moslem enemies "Roman fire"). The secret of this weapon is supposed to have been brought to the Byzantines by a refugee from Moslem-occupied Syria named Kallinikos (or Callinicus; the name is almost certainly a pseudonym - it means handsome winner, possibly a reference to the reward received for his invention). There was nothing particularly new about liquid fire - oil-based incendiaries had been used for some time. But this material had the astonishing property of burning on (or at least, when in) contact with water. Using it in combination with a spray device that allowed them to direct it against enemy ships, the Byzantines were able to utterly defeat the Arab fleet at the battle of Kyzikos in 678 A.D. - a remarkable achievemnt given that the Arabs had previously defeated the Byzantine fleet on an almost regular basis. The Byzantines had developed a decisive weapon, and they held it closely to keep their enemies from learning how to use or counter it. Their success with developing tactics to use the weapon, and in keeping others from using it, would serve them in good stead - Greek fire would be credited with many more victories - against the Moslems again in 717-718 A.D. and later against Russian attacks in 941 A.D. and 1043 A.D. The Moslems did not leave many commentaries about the use of this weapon against them, but the Rus, after their attack in 941 A.D., recorded the observation that "The Greeks possess something like the lightning in the heavens, and they released it and burned us. For this reason we did not conquer them."

While they didn't have Greek fire, the Moslems were adept with other oil-based incendiaries. In a siege of Mecca in 683 A.D. the Umayyads used catapaults to hurl naphtha-based incendiary projectiles against the defenders, accidentally setting the cloth covering of the Ka'bah on fire. In 813 A.D., Baghdad would be essentially destroyed by naphtha barrels thrown into the city, and in 1167 A.D. Cairo was destroyed by naphtha pots and bombs to deny it to the Crusaders.

Distillation of petroleum, to produce fractions ("white water naphtha") suited for incendiaries, was also known. A workshop for producing incendiary grenades, complete with a distilling furnace and a gasoline storage container, dating from the first half of the thirteenth century has been found in Hama, in Syria. The Book of Horsemanship and the Art of War, written by Najm al-Din Ahda in 1285, even tells how to build rockets with fire bomb warheads.

 

The Moslems seem to have avoided the intentional use of toxic additives in their flame weapons, perhaps because of injunctions in the Koran against poisoning the air and water.

 

Even without intention, disease traveled with war, both because of the poor sanitation that results and because war meant travel. The Crusades and the Arab expansion are both considered to have contributed greatly to the spread of smallpox.

Even nominally peaceful travel was a boon to the spread of disease. As Europe began to explore and colonize Africa and the New World, new diseases ravaged explorers, settlers, and natives. Venereal disease, apparently reimported from the New World and Yellow fever from Africa killed many. It was the mosquito-ridden swamps of the coastal regions of West Africa that gave rise to the term "The White Man's Grave." On the other hand, smallpox introduced by a single victim in the Cortez expedition killed 90% of the Aztecs of Mexico and in the far north the Eskimos were ravaged by epidemics of measles.

Forms of biological warfare were also practiced in the Middle Ages when the catapulting of diseased or putrefying corpses into castles became a feature of siege warfare. The earliest incidence of this which is well reported comes from the siege of Thun l'Eveque in 1340 during the Hundred Years War, where siege engines were used to (in the words of Jean Froissart, a contempory chronicler) "...cast in deed horses, and beestes stynking..." with the result that, as "...the ayre was hote as in the myddes of somer: the stynke and ayre was so abomynable," that the defenders felt they had to consider surrender. While no disease appears to have actually broken out, the defenders did subsequently withdraw.

While it may be argued that the intent of casting decomposing carcasses was simply to harass (which it certainly did) or perhaps to have something to throw during a brief shortage of the more usual stones, it seems almost certain that the aims included at least a hope on the part of the attackers that the defenders would be stricken with disease. After all, one of the prevailing theories of disease transmission of the period was that disease were caused by "bad air".

 

Legend has it, probably not completely correctly, that the Black Death that killed a quarter of Europe's population in the 14th Century was spread by refugees from the siege of the Genoese settlement of Kaffa in the Crimea when the Tartars used the bodies of plague victims as ammunition during the siege. Whatever the truth of this allegation, there is no question that the plague had a dramatic effect on both sides. Plague was already raging through the ranks of the Tartars when they started casting the bodies over the walls. Plague then also broke out among the defenders, leaving them too weakened and demoralized to take advantage of the situation (according to one chronicle, only one in several thousand retained health enough to flee).

 

Although there was no widespread interest in chemical warfare in the Renaissance, as with so many other things, the indefatigable Leonardo da Vinci seems to have done some thinking on it. He offered a proposal to

throw poison in the form of powder upon galleys. Chalk, fine sulfide of arsenic, and powdered verdegris may be thrown among enemy ships by means of small mangonels, and all those who, as they breathe, inhale the powder into their lungs will become asphyxiated.

He also considered the issue of protection. In his notes we find a description of a protective mask which would serve to shield the eyes, nose, and mouth (and lungs) of the user from dust and smoke - a more effective protection against the use of his toxic powders than the damp cloth originally proposed to protect their users from retaliation in kind.

As the Middle Ages gave way to the Rennaissance, gunpowder and firearms and artillery began to play a role in warfare and they came to dominate the battlefield. They eventually reduced the utility of castle walls to the point where even the most advanced fortifications could be reduced and broken by a choreographed set of maneuvers (provided that the defenders were unable to interrupt the dance). The rise of gunpowder weapons also produced an interest in chemistry, or at least in compounding mixtures for use in war.

Gunpowder-like mixtures - mixtures containing charcoal, sulfur, and saltpeter - were known in China by 1044 A.D., primarily as incendiaries, since the proportions were not right nor were they confined for a bang to occur. By 1232, the Chinese had developed rockets and a weapon called "Heaven-shaking Thunder", an iron bomb attached to a chain which could be lowered from the walls of a city to explode among attackers. By 1280 A.D., at least the knowledge that adding saltpeter to incendiary compositions made them work better was widespread, as a book on war engines written by a Syrian, one al-Hasan ar-Rammah, appeared which included instructions for its use and purification. At about the same time, a number of compositions which would explode, at least weakly, are described in such tomes as the Liber Ignium (Book of Fire) of Marchus Graecus. Very soon after this time the use of these materials to throw projectiles from what came to be known as guns began.

 

Initially, the projectiles were simply stones, but as time went by, a variety of new projectiles were developed. Explosive shells, with a powder charge ignited by a fuse lit just before firing it against the enemy appeared. And so did an incendiary shell that was called, in the proper terminolgy of artillery, the carcass, also called, by those that were not artillerymen (and some few who were), the stink pot. The carcass was a hollow metal shell with perforations for the emission of flame and flaming material, and, if one wonders why that would give rise to the sobriquot of stink pot, consider that the usual fill of a carcass included sulphur, tallow, rosin, turpentine, saltpeter, and antimony.

 

It was quickly observed that firing carcasses at an enemy could provide, at the least, considerable distraction as a result of the action of the fumes even when the primary goal of starting fires was not achieved. While never losing their primary function as starters of fires, a variety of fills were developed for carcasses that were intended to maximize the effects of the smoke. It is said that the gunners of the Imperial Artillery were particularly prone to the use of toxic fills during the Thirty Years War. The experience with noxious smokes would lead to speculation and some experimentation in the years to come.

The use of toxic projectiles was not viewed with total equanamity. German gunners were reported in 1650 to have pledged to "not construct any poisoned globes" and to "never employ them for the ruin and destruction of men, because the first inventors of our art thought such actions as unjust among themselves as unworthy of a man of heart and a real soldier."

The use of chemical weapons did not proceed unchecked. On the 27th of August, 1675, the French and the Germans concluded the Strasbourg Agreement, which included an article banning the use of "perfidious and odious" toxic devices (poisoned bullets). In 1672, during his siege of the city of Groningen, Christoph Bernhard van Galen, the Bishop of Münster, acquired a nickname, "Bommen Berend" (Bomber Berend), for his profligate use of artillery. Among the explosive and incendiary devices he used were some which had a fill including belladonna, intended to produce toxic fumes. The weapons failed to prove decisive, however, at least in part because they were used without taking wind direction into account. In the end, the Bishop had to withdraw, lifting the siege on the 28th of August, an event still celebrated in the city.

While the spread of gunpowder weapons had begun to get people thinking about the use of chemical technology in warfare, there was still little or no systematic thinking about, or use of, biological weapons. The possible impact of biological weapons had always been obvious to commanders who usually found disease to kill more men in the course of a campaign than did enemy fire. But the existing theories of how disease was transmitted, coupled with the lack of knowledge about how to direct a disease only against an enemy, made the use of disease as a weapon seem little more than a fantasy.

In 1714 an article in the Philosophical Transactions of the Royal Society would lay the groundwork for a change in how biological warfare was viewed. The article contained a description of a technique used by a physician, one Giacomo Pylarini of Smyrna, to confer some protection against smallpox. The technique, variolation, entailed taking some of the liquid from the pustules of a victim of a mild case of smallpox and rubbing it into a small scratch made on the person to be protected. Usually, the individual variolated would suffer a mild case of the disease and then be, on recovery, immune to further infection. There were two disadvantages - usually the case was mild, but not always and the variolated patient could spread the infection during the course of the (hopefully) mild case. However, the risk of death from variolation was felt to be acceptable when held against the problems that could result from uncontrolled infection (some estimates set mortality at 2-3%, which was still less than a tenth of the mortality rates seen without variolation), and conscientious quarantine would prevent problems with variolated patients spreading disease. The Chinese produced immunity to smallpox using a technique in which a dried powder of the material from a pustule was blown into a persons nose beginning in the Eleventh century.

The practice of variolation was introduced by Circassian traders to the Ottoman Empire, where it was practiced beginning no later than 1670.

 

Variolation would become especially popular in England, although not as a result of the 1714 article in the Philosophical Transactions (nor, for that matter, as a result of a second article that appeared in 1716). Its popularity is attributed to the actions of Lady Mary Wortley Montague, who had had been afflicted by smallpox and who had lost her brother to it. Lady Montague was married to Lord Edward Wortley Montague, who was the ambassador to the Sublime Porte of the Ottomans in Istanbul. There, Lady Montague observed the practice of variolation as practiced by the Turks and, determined not to have her family suffer as she had, directed the surgeon of the Embassy to learn the technique and, in March, 1718, to variolate her five year old son. After her return to England, she determined to promote the technique, and had Maitland variolate her four year old daughter in the presence of several physicians, including the king's physician. The royal interest was aroused, and Charles Maitland was given leave to perform what came to be known as the Royal Experiment, in which he variolated six condemned prisoners (who had been promised full pardons if they survived). When the prisoners survived (and were pardoned), further experiments were done on charity children. The safety of the procedure being established by these experiments, two of the king's grandchildren, the daughters of the Princess of Wales, were treated on April 17, 1722. After this the practice of variolation spread like wildfire, reaching even the rural areas of England by the 1740s.

Across the sea, in England's American colonies, the practice was accepted even earlier than in England. In 1721, the Reverend Cotton Mather had prevailed on Dr. Boyston to variolate some 244 people in an effort to halt a smallpox epidemic in Boston. When the deaths were tallied (six of the variolated against 844 of 5980 infected who had not been variolated) it was clear that variolation was the way to protect against the smallpox. By the 1750's, no less a personage than Benjamin Franklin was promoting the technique.

 

The goals of the practitioners of variolation, were, of course, benign. Smallpox was a terrible disease, killing from 20% to 60% of those afflicted (with a disproportionate effect on those younger than 5 years old - in one outbreak in Berlin, 98% of the children who caught the disease died). A significant number of the survivors of the disease were left blind as a result of corneal infection. At the least, a survivor would bear the scars of the disease.

But the popularization of variolation was a two-edged sword. Those living in the countries where variolation was popular could be presumed to know:

 

that smallpox in previously unexposed population could be devastating,

that smallpox could reliably be produced by exposing healthy individuals to materials obtained from smallpox victims,

that individuals seemed to become infected only once, and

that the dangers of smallpox could be significantly reduced by the practice of variolation.

In other words, if you had an army that was made up mostly of individuals who had already been exposed to smallpox, either naturally or through variolation, you would stand to gain if smallpox were to be introduced to an opposing army which was not similarly protected. And, if you had access to smallpox cases, then you could acquire materials that would allow you to be sure that you could expose an actual or potential enemy to the disease.

To Sundries got to Replace in kind those which were taken from people in the Hospital to Convey the Smallpox to the Indians

- line item in the ledger for Ft. Pitt, June, 1763

In 1763, during the Pontiac Rebellion, Captain Simon Ecuyer, the commanding officer of Fort Pitt, found himself in a difficult situation. The indians were pressing hard - three forts in the Ohio River watershed had been lost, and many settlers had come to Fort Pitt seeking safety. The Fort was crowded and uncomfortable, and smallpox had appeared among the refugees. On June the twenty-third, two Delaware indians appeared at the fort, asking for a parley with Alexander McKee, the Assistant Deputy Superintendent of Induan Affairs for the Crown. On the twenty-fourth, Captain Ecuyer, along with a delegation including Mr. McKee and also William Trent (who was the commander of a local civilian militia) met with the indians, who professed a desire to avoid conflict and called for the evacuation of Fort Pitt, indicating that, if this were done quickly, it could be done peacefully. Captain Ecuyer declined to evacuate the fort, claiming that three large armies were coming to his aid. The indians indicated that for their part they hoped for friendship (a hope that the British, at least, were doubtless suspicious of, since the history of wars with the American indians had been full of spurious offers of safe conduct), and at this point, as Mr. Trent records in his journal [2], "Out of our regard for them, we gave them two Blankets and a Handkerchief out of the Small Pox Hospital. I hope it will have the desired effect" In the event, the Delaware were to suffer severely from an epidemic of smallpox, although the infected materials may have been only one of several sources of infection.

The natives of the New World also used chemical and biological weapons. In South America, the smoke from burning chili peppers was used boh in local conflicts and against the Portuguese as a sort of tear gas, while in the North, there are several incidents that suggest that the Indians may also have tried to initiate smallpox outbreaks among the European soldiers and settlers. The documentation that survives, including the ledgers (which had to be approved by British authorities up to the level of General Gage, the Commander-in-Chief of British forces in America), makes it clear that this action was not seen as something extraordinary, or an action taken under unusual circumstances by a local commander. In fact, letters survive from a correspondence in July of 1763 between General Sir Jeffery Amherst (then the British Commander-in-Chief) and Colonel Henry Bouquet, who was leading a relief force to Ft. Pitt, that the use of smallpox as a weapon against the indians was receiving general consideration. In a letter which seems to have been written shortly after he learned that smallpox had broken out at the fort, Genral Amherst suggests asks Colonel Bouqet "Could it not be contrived to send the Small Pox among those disaffected tribes of Indians?" On the thirteenth of July, Colonel Bouqet, on his way to Ft. Pitt, replies "I will try to inoculate the...with some blankets that may fall in their hands, and take care not to get the disease myself." This independent mirroring of the use of the smallpox, down to the method of delivering the infectious particles, makes it seem likely that the use of smallpox had received some attention in military circles prior to the event. Indeed, there is some evidence, although none is conclusive, that this was not the first time smallpox was employed against the indians. Certainly the inclusion of the line item noted above in his accounts makes it clear that Captain Ecuyer was not concerned that there would be any censure for his actions.

Fort Pitt was not the only time that informed attempts at biological warfare were made in the New World in the second half of the 1700s, simply the best documented one. Among the most significant would be those by the British during the American Revolution, not for their effect, but for the response they provoked.

In April of 1775, the British in Boston found themselves facing both the Continental Army and a smallpox epidemic. Reasonably enough, they began to variolate their troops. Less reasonably, they began to variolate civilians fleeing the city. While there is no documentation surviving that demonstrates the British intention in this instance, it was well known that those variolated became infectious. General Washington, the commander of the Continental Army, wrote that he believed that "...the enemy intended spreading the Small pox amongst us". He had been encouraged in this belief by the stories of British deserters, about which he was skeptical until an outbreak of the disease among the evcacuees convinced him. He delayed his attack, regarding the smallpox in Boston as "a weapon of Defence" being used by the British. When it was finally evacuated by the British, Washington advanced with great care, fearing the exposure of his troops to the disease.

Washington had himself been a victim of smallpox, and in 1776 saw his attack on Quebec fail in large part because many soldiers were affected by an outbreak of smallpox (which many believed, albeit with small evidence, to have been the work of the British, judging by the testimony given to a Congressional hearing on the attack). He knew what the disease could do, and had come to regard it as "the greatest enemy of the Continental Army". But he also knew what to do - variolate. On January 6, 1777 he issued to Dr. William Shippen, Jr., Director General of the Hospitals and Physician in Chief to the Army, an order to inoculate all the Continental troops and the new recruits, also advising him to keep "the matter as secret as possible". danger was past.

 

Surviving letters indicate at least the hope of causing infection among the Rebels on several other occasions. One of the most significant is that of General Alexander Leslie, who notes in a missive directed to General Cornwallis dated July 13, 1781 that more than "700 Negroes are come down the river in the Small Pox." and that he intends to "distribute them about the Rebell plantations."

The idea of speading smallpox to the rebels was discussed openly. Robert Donkin's 1777 book, "Military Collections and Remarks", published in New York, contains a footnote picturesquely suggesting that the rebellious Americans would disband in fear if the British should " Dip arrows in matter of smallpox and twang them at the American rebels, in order to inoculate them."

 

For the first time in history, measures had been taken to secure an army against, not only the very real risk of natural infection, but also against the risk of a deliberate biological attack. And they worked - after 1777 the Continental Army was never hampered by smallpox in its operations again.

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Let me inform you all of something. There are two types of smallpox. variola major and variola minor. Minor is more rampant because of the ability of the diseased to be ambulatory. You are more likely to recover.

 

BTW the chinese invented psychological warfare too....

 

The chinese also invented the first "vaccine"

 

you had to snort cow hide from a cow that had cowpox. You would be immune to smallpox.

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